FUNCTIONALLY OVERLAPPING INTRA- AND EXTRALYSOSOMAL PATHWAYS PROMOTE BIS(MONOACYLGLYCERO)PHOSPHATE SYNTHESIS IN MAMMALIAN CELLS

Functionally overlapping intra- and extralysosomal pathways promote bis(monoacylglycero)phosphate synthesis in mammalian cells

Abstract Bis(monoacylglycero)phosphate (BMP) is a major phospholipid constituent of intralumenal membranes in late endosomes/lysosomes, where it regulates the degradation 5 Piece Reclining Sectional with Power and sorting of lipid cargo.Recent observations suggest that the Batten disease-associated protein CLN5 functions as lysosomal BMP synthase.H

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A DNA barcode library for ground beetles of Germany: the genus Agonum Bonelli, 1810 (Insecta, Coleoptera, Carabidae)

The ground beetle genus Agonum Bonelli, 1810 is a large genus of the tribe Platynini with many species that show high amounts of intraspecific variations, making a correct identification challenging.As part of the German Barcode of Life initiative, this publication provides a comprehensive DNA barcode library for species of Agonum that are reported

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Tooth mineralization and histology patterns in extinct and extant snaggletooth sharks, Hemipristis (Carcharhiniformes, Hemigaleidae)-Evolutionary significance or ecological adaptation?

Shark jaws exhibit teeth that are arranged into distinct series and files and display great diversities in shapes and structures, which not only is related to their function (grasping, cutting, crushing) during feeding, but also bear a strong phylogenetic signal.So far, most research on the relationship between shark teeth and feeding ecology and s

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